1. To be in charge of.
2. To command with authority.
3. To give directions to; point somebody into a certain direction; SYN. point.
4. To guide the actors in (plays and films).

ETYM French orienter. Related to Orientate.
1. To be oriented; SYN. point.
2. To cause to point.
3. To determine one's position with reference to another point; SYN. orientate.