1. To deplete; SYN. exhaust, sap, tire, use up.
2. To injure or kill by running over, as with a car; SYN. run over.
3. To move downward
4. To pursue until captured:
5. To trace; SYN. check out.
6. When vehicles or people driving vehicles hit and injure or kill someone, they run that person down.
7. When you discuss or review items on a list from the first to the last, you run down the list.
8. When batteries or machines run down or are run down by someone, they gradually lose power or energy.