ETYM Old Eng. disese, Old Fren. desaise; des- (Latin dis-) + aise ease. Related to Ease.
Any condition that impairs the normal state of an organism, and usually alters the functioning of one or more of its organs or systems. A disease is usually characterized by a set of specific symptoms and signs, although these may not always be apparent to the sufferer. Diseases may be inborn (see congenital disease) or acquired through infection, injury, or other cause. Many diseases have unknown causes.
An impairment of health or a condition of abnormal functioning.