ETYM French, from fatiguer to fatigue, Latin fatigare; cf. Latin affatim sufficiently.
1. Temporary loss of strength and energy resulting from hard physical or mental work; SYN. weariness, tiredness.
2. A lack of vitality; SYN. anemia, anaemia.
3. (Of materials (especially metals)) the state of being weakened by long stress.

To tire with labor or any bodily or mental exertion; to burden with labor; to exhaust the strength or endurance of; SYN. jade; tire; weary.