ETYM Old Eng. ache, AS. aece, ece, from acan to ache. Related to Ache.
A dull persistent (usually moderately intense) pain; SYN. aching.

1. Morally objectionable behavior; SYN. immorality, wickedness, iniquity.
2. That which causes harm or destruction or misfortune
3. The quality of being morally wrong in principle or practice; SYN. evilness.
What is bad for, or harmful to, human beings or animals. Evil is traditionally divided into moral and natural evil. Moral evil originates in human action, whereas natural evil originates independently of human action—for instance, earthquakes or epidemics. The problem of evil is the difficulty of explaining the existence of evil if the world was created by a perfect and omnipotent God.
Evil can also be seen as illusory or real; and, when real, evil can be either a positive thing (the position of Manichaeism) or a negative thing— the absence of goodness, just as darkness is the absence of light (the position of St Augustine of Hippo).

ETYM From Ill.
Impairment of normal physiological function affecting part or all of an organism; SYN. malady, sickness.

ETYM Old Eng. peine, French peine, from Latin poena, penalty, punishment, torment, pain.
(Homonym: pane).
1. A bodily sensation of acute discomfort; SYN. painful sensation.
2. A symptom of some physical hurt or disorder; SYN. hurting.
3. Emotional distress; a fundamental feeling that people try to avoid; SYN. painfulness.
4. A bothersome annoying person; SYN. pain in the neck, nuisance.
Sense that gives an awareness of harmful effects on or in the body. It may be triggered by stimuli such as trauma, inflammation, and heat. Pain is transmitted by specialized nerves and also has psychological components controlled by higher centers in the brain. Drugs that control pain are known as painkillers or analgesics.
A pain message to the brain travels along the sensory nerves as electrical impulses. When these reach the gap between one nerve and another, biochemistry governs whether this gap is bridged and may also either increase or decrease the attention the message receives or modify its intensity in either direction. The main type of pain transmitter is known simply as “substance p”, a neuropeptide concentrated in a certain area of the spinal cord. Substance P has been found in fish, and there is also evidence that the same substances that cause pain in humans (for example, bee venom) cause a similar reaction in insects and arachnids (for instance, spiders).
Since the sensation of pain is transmitted by separate nerves from that of fine touch, it is possible in diseases such as syringomyelia to have no sense of pain in a limb, yet maintain a normal sense of touch. Such a desensitized limb is at great risk of infection from unnoticed cuts and abrasions.

ETYM AS. seócness.
Disease; illness; the cause of a loss of health.