Khorana | engleski leksikon


muški rodlično ime


(1922-) Indian-born US biochemist who in 1976 led the team that first synthesized a biologically active gene. In 1968 he shared the Nobel Prize for Physiology or Medicine for research on the chemistry of the genetic code and its function in protein synthesis. Khorana's work provides much of the basis for gene therapy and biotechnology.
Khorana was born in Raipur in the Punjab, now in Pakistan. He studied at Punjab University; in the UK at Liverpool; and in Switzerland at Zürich; returning to Britain 1950 to work at Cambridge. He has held academic posts in the US and Canada, becoming professor at the University of Wisconsin 1962 and at the Massachusetts Institute of Technology 1970.
Khorana systematically synthesized every possible combination of the genetic signals from the four nucleotides known to be involved in determining the genetic code. He showed that a pattern of three nucleotides, called a triplet, specifies a particular amino acid (the building blocks of proteins). He further discovered that some of the triplets provided punctuation marks in the code, marking the beginning and end points of protein synthesis.
Khorana has also synthesized the gene for bovine rhodopsin, the pigment in the retina responsible for converting light energy into electrical energy.

Reč dana


pridev, medicina


muški rod, geografija


muški rod, životinja


muški rod, anatomija